Modelling the impact of vaccination and environmental transmission on the dynamics of monkeypox virus under Caputo operator

Author:

Addai Emmanuel12,Ngungu Mercy3,Omoloye Musibau Abayomi4,Marinda Edmore3

Affiliation:

1. College of Biomedical Engineering, Taiyuan University of Technology, Shanxi Taiyuan 030024, China

2. Department of Mathematics, Taiyuan University of Technology, Shanxi Taiyuan 030024, China

3. Human Sciences Research Council (HSRC), South Africa

4. Department of Mathematics and Computer Science, Elizade University, Ilara-Mokin, Ondo State, Nigeria

Abstract

<abstract><p>In this study, we examine the impact of vaccination and environmental transmission on the dynamics of the monkeypox. We formulate and analyze a mathematical model for the dynamics of monkeypox virus transmission under Caputo fractional order. We obtain the basic reproduction number, the conditions for the local and global asymptotic stability for the disease-free equilibrium of the model. Under the Caputo fractional order, existence and uniqueness solutions have been determined using fixed point theorem. Numerical trajectories are obtained. Furthermore, we explored some of the sensitive parameters impact. Based on the trajectories, we hypothesised that the memory index or fractional order could use to control the Monkeypox virus transmission dynamics. We observed that if the proper vaccination is administrated, public health education is given, and practice like personal hygiene and proper disinfection spray, the infected individuals decreases.</p></abstract>

Publisher

American Institute of Mathematical Sciences (AIMS)

Subject

Applied Mathematics,Computational Mathematics,General Agricultural and Biological Sciences,Modeling and Simulation,General Medicine

Reference40 articles.

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3. E. M. Bunge, B. Hoet, L. Chen, F. Lienert, H. Weidenthaler, L. R. Baer, et al., The changing epidemiology of human monkeypox-A potential threat? A systematic review, PLoS Negl. Trop. Dis., 16 (2022), e0010141. https://doi.org/10.1371/journal.pntd.0010141

4. Centers for Disease Control and Prevention (CDC), 2022 Mpox outbreak global map, 2022. Available from: https://www.cdc.gov/poxvirus/monkeypox/response/2022/world-map.html.

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