Insertional Mutagenesis of the Mouse Acid Ceramidase Gene Leads to Early Embryonic Lethality in Homozygotes and Progressive Lipid Storage Disease in Heterozygotes

Author:

Li Chi-Ming,Park Jae-Ho,Simonaro Calogera M.,He Xingxuan,Gordon Ronald E.,Friedman Adriana-Haimovitz,Ehleiter Desiree,Paris Francois,Manova Katia,Hepbiloikler Stefan,Fuks Zvi,Sandhoff Konrad,Kolesnick Richard,Schuchman Edward H.

Publisher

Elsevier BV

Subject

Genetics

Reference29 articles.

1. Enzymic hydrolysis and synthesis of ceramide;Gatt;J. Biol. Chem.,1963

2. Enzymatic hydrolysis of sphingolipids. 1. Hydrolysis and synthesis of ceramides by an enzyme from rat brain;Gatt;J. Biol. Chem.,1966

3. Ceramidase: enzymology and metabolic roles;Hassler;Adv. Lip. Res.,1993

4. Moser, H. W., Linke, T., Fensom, A. H., Levade, T., and Sandhoff, K.2001. Acid ceramidase deficiency: Farber lipogranulomatosis. In The Metabolic & Molecular Basis of Inherited DiseaseC. R. Scriver, A. L. Beaudet, D. Valle, and W. S. Sly, Eds., pp. 3573–3588. McGraw-Hill, New York.

5. Function of ceramide in coordinating cellular responses to stress;Hannun;Science,1996

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