Geranylgeranyl as Well as Farnesyl Moiety Is Transferred to Ras p21 Overproduced in Adrenocortical Cells Transformed by c-Ha-rasEJOncogene
Author:
Publisher
Elsevier BV
Subject
Cell Biology,Molecular Biology,Biochemistry,Biophysics
Reference24 articles.
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4. A CAAX or a CAAL motif and a second signal are sufficient for plasma membrane targeting of ras proteins.
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2. Prenylation is not necessary for endogenous Ras activation in non-malignant cells;Journal of Cellular Biochemistry;2006
3. Farnesyl transferase inhibitors: the next targeted therapies for breast cancer?;Endocrine-related cancer;2004-06
4. Combination of the novel farnesyltransferase inhibitor RPR130401 and the geranylgeranyltransferase-1 inhibitor GGTI-298 disrupts MAP kinase activation and G1 -S transition in Ki-Ras-overexpressing transformed adrenocortical cells;FEBS Letters;1999-10-25
5. Inhibiting geranylgeranylation blocks growth and promotes apoptosis in pulmonary vascular smooth muscle cells;American Journal of Physiology-Lung Cellular and Molecular Physiology;1998-07-01
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