Modeling Activation and Desensitization of G-Protein Coupled Receptors Provides Insight into Ligand Efficacy

Author:

RICCOBENE TODD A,OMANN GENEVA M,LINDERMAN JENNIFER J

Publisher

Elsevier BV

Subject

Applied Mathematics,General Agricultural and Biological Sciences,General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,Modelling and Simulation,General Medicine,Statistics and Probability

Reference41 articles.

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3. Agonist-induced desensitization of D1-dopamine receptors linked to adenyl cyclase activity in cultured NS20Y neuroblastoma cells;BARTON;Mol. Pharm.,1990

4. β -Adrenergic receptor kinase: activity of partial agonists for stimulation of adenylate cyclase correlates with ability to promote receptor phosphorylation;BENOVIC;J. Biol. Chem.,1988

5. Mammalian RGS proteins: barbarians at the gate;BERMAN;J. Biol. Chem.,1998

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