An Overview of Biofilm as a Virulence Factor for Bacteria to Survive in the Harsh Environment

Abstract

Microbial biofilms are collections of grouped microbial cells enmeshed in an extracellular polymeric substances (EPS) matrix that they have self-assembled. Biofilms are resistant to harsh environments and can serve as "protective clothing" for bacteria by shielding them from ultraviolet (UV) radiation, extreme temperatures, pH ranges, high salinity, high pressure, inadequate nutrition, antibiotics, etc. Research on biofilms in recent years has mostly concentrated on biofilm-associated illnesses and methods for eradicating microbial biofilms.