Different Anti-Oxidant Effects of Thioredoxin 1 and Thioredoxin 2 in Retinal Epithelial Cells

Author:

Sugano Eriko1,Isago Hitomi1,Murayama Namie1,Tamai Makoto2,Tomita Hiroshi134

Affiliation:

1. Department of Chemistry and Bioengineering, Faculty of Engineering, Graduate School of Engineering, Iwate University

2. School of Medicine, Tohoku University

3. Graduate School of Medicine, Tohoku University

4. Clinical Research, Innovation and Education Center, Tohoku University Hospital

Publisher

Japan Society for Cell Biology

Subject

Cell Biology,Molecular Biology,Physiology,General Medicine

Reference30 articles.

1. Abe, T., Tomita, H., Ohashi, T., Yamada, K., Takeda, Y., Akaishi, K., Yoshida, M., Sato, M., and Tamai, M. 1999. Characterization of iris pigment epithelial cell for auto cell transplantation. Cell Transplant., 8: 501–510.

2. Nuclear Factor-κB — A Pivotal Transcription Factor in Chronic Inflammatory Diseases

3. Beatty, S., Koh, H., Phil, M., Henson, D., and Boulton, M. 2000. The role of oxidative stress in the pathogenesis of age-related macular degeneration. Surv. Ophthalmol., 45: 115–134.

4. Cai, J., Nelson, K.C., Wu, M., Sternberg, P.Jr., and Jones, D.P. 2000. Oxidative damage and protection of the RPE. Prog. Retin. Eye Res., 19: 205–221.

5. Caprioli, J., Munemasa, Y., Kwong, J.M., and Piri, N. 2009. Overexpression of thioredoxins 1 and 2 increases retinal ganglion cell survival after pharmacologically induced oxidative stress, optic nerve transection, and in experimental glaucoma. Trans. Am. Ophthalmol. Soc., 107: 161–165.

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