Retinal blood vessels detection for diabetic retinopathy with Ridgelet transform and convolution neural network

Abstract

Applying machine learning in life sciences, especially diagnostics, has become a key area of focus for researchers. Combining machine learning with traditional algorithms provides a unique opportunity of providing better solutions for the patients. In this paper, we present study results of applying the Ridgelet Transform method on retina images to enhance the blood vessels, then using machine learning algorithms to identify cases of Diabetic Retinopathy (DR). The Ridgelet transform provides better results for line singularity of image function and, thus, helps to reduce artefacts along the edges of the image. The Ridgelet Transform method, when compared with earlier known methods of image enhancement, such as Wavelet Transform and Contourlet Transform, provided satisfactory results. The transformed image using the Ridgelet Transform method with pre-processing quantifies the amount of information in the dataset. It efficiently enhances the generation of features vectors in the convolution neural network (CNN). In this study, a sample of fundus photographs was processed, which was obtained from a publicly available dataset. In pre-processing, first, CLAHE was applied, followed by filtering and application of Ridgelet transform on the patches to improve the quality of the image. Then, this processed image was used for statistical feature detection and classified by deep learning method to detect DR images from the dataset. The successful classification ratio was 98.61%. This result concludes that the transformed image of fundus using the Ridgelet Transform enables better detection by leveraging a transform-based algorithm and the deep learning.