Synthesis of Carbon Dots from PEG6000 and Papain for Fluorescent and Doxycycline Sensing

Author:

Feng Yuanjiao1ORCID,Tan Lihong1,Tang Qian1,Zhong Wenwu1,Yang Xiaoming2ORCID

Affiliation:

1. Chongqing Medical and Pharmaceutical College, Chongqing 401331, P. R. China

2. College of Pharmaceutical Sciences, State Key Laboratory of Silkworm Genome Biology, Southwest University, Chongqing 400715, P. R. China

Abstract

Herein, a simple-green road for preparing carbon dots (CDs) from the mixture of PEG6000 and papain with approving fluorescence has been successfully developed for the first time. Meanwhile, the current CDs were characterized by analytical means such as fluorescence, UV visible spectrophotometer, HR-TEM, XPS and FTIR and so on. Afterwards, this kind of CDs were employed for analyzing doxycycline (DC) relying on the mechanism that the functional group of DC had interactions with CDs, hence, leading to the fluorescence quenching. Also, this DC analytical method mentioned here permitted in a linear range of [Formula: see text][Formula: see text]mol/L-[Formula: see text][Formula: see text]mol/L as well as a detection limit of 18[Formula: see text]nM at a signal-to-noise ratio (S/N) of 3. More importantly, the CDs prepared here were still explored for milk real samples, indicating their potential for broadening avenues towards other various applications.

Funder

Opening Research Project

Fundamental Research Funds for the Central Universities

Innovative Project on Designing and Screening Drug Candidates of Chongqing

Publisher

World Scientific Pub Co Pte Lt

Subject

Condensed Matter Physics,General Materials Science

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