THE GEANT4-DNA PROJECT-Reference-Cited by-同舟云学术

THE GEANT4-DNA PROJECT

Published:2010-06 Issue:02 Volume:01 Page:157-178
ISSN:1793-9623
Container-title:International Journal of Modeling, Simulation, and Scientific Computing
language:en
Short-container-title:Int. J. Model. Simul. Sci. Comput.

Author:

INCERTI S.¹,BALDACCHINO G.²,BERNAL M.³,CAPRA R.,CHAMPION C.⁴,FRANCIS Z.⁵,GUÈYE P.⁶,MANTERO A.¹,MASCIALINO B.⁷,MORETTO P.¹,NIEMINEN P.⁸,VILLAGRASA C.⁵,ZACHARATOU C.⁹

Affiliation:

1. Université Bordeaux 1, CNRS/IN2P3, Centre d'Etudes Nucléaires de Bordeaux-Gradignan, CENBG, Chemin du solarium, BP 120, 33175 Gradignan, France

2. CEA Saclay, IRAMIS, UMR3299 CEA-CNRS SIS2M, Laboratoire de Radiolyse, F-91191 Gif-sur-Yvette Cedex, France

3. Departamento de Física, Universidad Simon Bolívar, Venezuela

4. Université Paul Verlaine-Metz, Laboratoire de Physique, Moléculaire et des Collisions, 1 Boulevard Arago, Technopôle 2000, 57078 Metz, France

5. IRSN, Institut de Radioprotection et de Sureté Nucléaire, BP17, 92262 Fontenay-aux-Roses, France

6. Hampton University, Physics Department, Hampton VA 23668, USA

7. Karolinska Institutet, Box 260, S-171-76, Stockholm, Sweden

8. ESA-ESTEC, 2200 AG Noordwijk, The Netherlands

9. Niels Bohr Institute, Blegdamsvej 17, 2100 Copenhagen, Denmark

Abstract

The Geant4-DNA project proposes to develop an open-source simulation software based and fully included in the general-purpose Geant4 Monte-Carlo simulation toolkit. The main objective of this software is to simulate biological damages induced by ionizing radiations at the cellular and sub-cellular scale. This project was originally initiated by the European Space Agency for the prediction of the deleterious effects of radiations that may affect astronauts during future long duration space exploration missions. In this paper, the Geant4-DNA collaboration presents an overview of the whole on-going project, including its most recent developments that are available in the Geant4 toolkit since December 2009 (release 9.3), as well as an illustration example simulating the direct irradiation of a biological chromatin fiber. Expected extensions involving several research domains, such as particle physics, chemistry and cellular and molecular biology, within a fully interdisciplinary activity of the Geant4 collaboration are also discussed.

Publisher

World Scientific Pub Co Pte Lt

Subject

Computer Science Applications,Modeling and Simulation

Link

https://www.worldscientific.com/doi/pdf/10.1142/S1793962310000122

Reference18 articles.

1. A molecular theory of cell survival

2. Geant4 Physics Processes for Microdosimetry Simulation: Design Foundation and Implementation of the First Set of Models

3. Simulation of DNA fragment distributions after irradiation with photons

4. Geant4—a simulation toolkit

5. Geant4 developments and applications

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