A Bayesian network model for predicting type 2 diabetes risk based on electronic health records

Author:

Xie Jiang1,Liu Yan1,Zeng Xu1,Zhang Wu1,Mei Zhen2

Affiliation:

1. School of Computer Engineering and Science, Shanghai University, 99 Shangda Road, Shanghai 200444, China

2. Manifold Data Mining Inc., 220 Duncan Mill Road, Suite 519, Toronto, ON M3B 3J5, Canada

Abstract

An extensive, in-depth study of diabetes risk factors (DBRF) is of crucial importance to prevent (or reduce) the chance of suffering from type 2 diabetes (T2D). Accumulation of electronic health records (EHRs) makes it possible to build nonlinear relationships between risk factors and diabetes. However, the current DBRF researches mainly focus on qualitative analyses, and the inconformity of physical examination items makes the risk factors likely to be lost, which drives us to study the novel machine learning approach for risk model development. In this paper, we use Bayesian networks (BNs) to analyze the relationship between physical examination information and T2D, and to quantify the link between risk factors and T2D. Furthermore, with the quantitative analyses of DBRF, we adopt EHR and propose a machine learning approach based on BNs to predict the risk of T2D. The experiments demonstrate that our approach can lead to better predictive performance than the classical risk model.

Publisher

World Scientific Pub Co Pte Lt

Subject

Condensed Matter Physics,Statistical and Nonlinear Physics

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