CORTICAL EXCITABILITY AND REFRACTORY EPILEPSY: A THREE-YEAR LONGITUDINAL TRANSCRANIAL MAGNETIC STIMULATION STUDY-Reference-Cited by-同舟云学术

CORTICAL EXCITABILITY AND REFRACTORY EPILEPSY: A THREE-YEAR LONGITUDINAL TRANSCRANIAL MAGNETIC STIMULATION STUDY

Published:2012-12-30 Issue:01 Volume:23 Page:1250030
ISSN:0129-0657
Container-title:International Journal of Neural Systems
language:en
Short-container-title:Int. J. Neur. Syst.

Author:

BADAWY RADWA A. B.¹²³,JACKSON GRAEME D.¹²³,BERKOVIC SAMUEL F.¹²³,MACDONELL RICHARD A. L.¹²³

Affiliation:

1. Department of Neurology, Austin Health, Heidelberg, Epilepsy Research Centre, Australia

2. Department of Medicine, University of Melbourne, Brain Research Institute, Australia

3. Florey Neuroscience Institutes Heidelberg West, Victoria, Australia

Abstract

Transcranial magnetic stimulation was used to study the effect of recurrent seizures on cortical excitability over time in epilepsy. 77 patients with firm diagnoses of idiopathic generalized epilepsy (IGE) or focal epilepsy were repeatedly evaluated over three years. At onset, all groups had increased cortical excitability. At the end of follow-up the refractory group was associated with a broad increase in cortical excitability. Conversely, cortical excitability decreased in all seizure free groups after introduction of an effective medication.

Publisher

World Scientific Pub Co Pte Lt

Subject

Computer Networks and Communications,General Medicine

Link

https://www.worldscientific.com/doi/pdf/10.1142/S012906571250030X

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