The Improved Element-Free Galerkin Method for Diffusional Drug Release Problems

Abstract

By using the improved moving least-square (IMLS) approximation to present the shape function, the improved element-free Galerkin (IEFG) method is investigated to solve diffusional drug release problems in this paper. In order to get the discretized equation system, Galerkin weak form of a diffusional drug release problem is used with applying essential boundary conditions using the penalty method. The difference method is applied for discretization of time domain. Then the formulae of IEFG method for solving diffusional drug release problems are presented. Three numerical example problems are given to study the convergence of solutions of IEFG method in this paper. The influences of scale parameters of influence domain, penalty factor and node distribution on the accuracy of the solutions of IEFG method are discussed. Compared with finite element method, the correctness of IEFG method in this paper is shown.