A particle method for non-local advection–selection–mutation equations

Author:

Alvarez Frank Ernesto12,Guilberteau Jules3

Affiliation:

1. Le Centre de Recherche en Mathématiques de la Décision (CEREMADE), Centre National de la Recherche Scientifique (CNRS) est une unit mixte, de Recherche (UMR) No. 7534, PSL University, Université Paris-Dauphine, Place du Maréchal De Lattre De Tassigny, Paris CEDEX 16, 75775, France

2. GMM, INSA Toulouse, 135 Avenue de Rangueil, Toulouse, 31000, France

3. Laboratoire Jacques-Louis Lions (LJLL), Centre National de la Recherche Scientifique (CNRS) Sorbonne Université, Université Paris Cité, Inria, F-75005 Paris, France

Abstract

The well-posedness of a non-local advection–selection–mutation problem deriving from adaptive dynamics models is shown for a wide family of initial data. A particle method is then developed, in order to approximate the solution of such problem by a regularized sum of weighted Dirac masses whose characteristics solve a suitably defined ODE system. The convergence of the particle method over any finite interval is shown and an explicit rate of convergence is given. Furthermore, we investigate the asymptotic-preserving properties of the method in large times, providing sufficient conditions for it to hold true as well as examples and counter-examples. Finally, we illustrate the method in two cases taken from the literature.

Funder

European Union's Horizon 2020 research and innovation programme under the Marie Sk lodowska-Curie

Publisher

World Scientific Pub Co Pte Ltd

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1. Phenotype divergence and cooperation in isogenic multicellularity and in cancer;Mathematical Medicine and Biology: A Journal of the IMA;2024-06

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