DETERMINANTS OF HEALTH STATUS AMONG PATIENTS WITH KNEE OR HIP OSTEOARTHRITIS: THE ROLE OF DEMOGRAPHIC, CLINICAL AND HEALTH RELATED QUALITY OF LIFE VARIABLES

Abstract

Osteoarthritis (OA) is a common chronic disease especially among older adults and has a considerable negative impact on health status (HS). This study investigated associations between demographic, clinical and health related quality of life (HRQOL) factors and the HS of patients with knee or hip OA. We surveyed a convenience sample of 356 patients from two general hospitals in Tehran, Iran. The short form health survey (SF-12), EuroQol (EQ-5D) and a demographic questionnaire were administered. Clinical variables such as body mass undex (BMI), duration of disease and radiographic evidence of the severity of OA were also collected. Two hierarchical regression models identified independent factors related to HS. The mean age of participants was 63.0 (SD, 12.3) and majority were female (90.7%). More than three-quarters were overweight or obese and over two-thirds had an OA severity grade of 3 or 4 based on Kellgren–Lawrence scale. The mean score on the physical and mental components of the SF-12 were 30.50 (SD, 9.63) and 44.38 (SD, 8.64), respectively. The mean scores for HS were 0.47 (SD, 0.34) on the EQ-5D and 63.23 (SD 17.58) on the EQ-VAS. Residence, duration of disease, BMI, OA joint, pain, vitality and mental health (MH) were identified as significant predictors of HS. Future studies are needed to better understand factors that may affect the HS of patients with knee or hip OA.