Affiliation:
1. Department of Mathematics and Statistics, Indian Institute of Technology, Kanpur 208016, India
Abstract
A numerical study is carried out for the singularly perturbed generalized Hodgkin–Huxley equation. The equation is nonlinear which mimics the ionic processes at a real nerve membrane. A small parameter called singular perturbation parameter is introduced in the highest order derivative term. Keeping other parameters fixed, as this singular perturbation parameter approaches to zero, a boundary layer occurs in the solution. Three-step Taylor Galerkin finite element method is employed on a piecewise uniform Shishkin mesh to solve the equation. To procure more accurate temporal differencing, the method employs forward-time Taylor series expansion including time derivatives of third order which are evaluated from the governing singularly perturbed generalized Hodgkin–Huxley equation. This yields a generalized time-discretized equation which is successively discretized in space by means of the standard Bubnov–Galerkin finite element method. The method is third-order accurate in time. The code based on the purposed scheme has been validated against the cases for which the exact solution is available. It is also observed that for the Singularly Perturbed Generalized Hodgkin–Huxley equation, the boundary layer in the solution manifests not only by varying the singular perturbation parameter but also by varying the other parameters appearing in the model.
Publisher
World Scientific Pub Co Pte Lt
Subject
Computer Science Applications,Modeling and Simulation
Cited by
2 articles.
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