Eigen's Error Threshold and Mutational Meltdown in a Quasispecies Model

Author:

Bagnoli F.12,Bezzi M.34

Affiliation:

1. Dipartimento di Matematica Applicata, Università di Firenze, via S. Marta, 3 I-50139, Firenze, Italy

2. INFN and INFM, sez. di Firenze, Italy

3. Dipartimento di Fisica, Università di Bologna, Via Irnerio, 46, I-40126 Bologna, Italy

4. INFN, sez. di Bologna, Italy

Abstract

We introduce a toy model for interacting populations connected by mutations and limited by a shared resource. We study the presence of Eigen's error threshold and mutational meltdown. The phase diagram of the system shows that the extinction of the whole population due to mutational meltdown can occur well before an eventual error threshold transition.

Publisher

World Scientific Pub Co Pte Lt

Subject

Computational Theory and Mathematics,Computer Science Applications,General Physics and Astronomy,Mathematical Physics,Statistical and Nonlinear Physics

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