VULNERABILITY TO REENTRY, AND DRIFT, STABILITY AND BREAKDOWN OF SPIRAL WAVES IN A LINEAR GRADIENT OF GK IN A LUO–RUDY 1 VIRTUAL VENTRICULAR TISSUE

Abstract

The vulnerable window in a heterogeneous virtual LRl cardiac tissue, with a linear gradient in GK, is wider when following propagation down the gradient, towards tissue with longer action potential duration, than when following propagation up the gradient. Spiral wave solutions in a uniform linear gradient in GK drift, with a velocity component along the gradient of the order of mm/s, towards tissue with a longer APD.