New Algorithms for Hierarchical Optimization in Kidney Exchange Programs

Author:

Delorme Maxence1ORCID,García Sergio2ORCID,Gondzio Jacek2ORCID,Kalcsics Jörg2ORCID,Manlove David3ORCID,Pettersson William3ORCID

Affiliation:

1. Department of Econometrics and Operations Research, Tilburg University, 5037 AB Tilburg, Netherlands;

2. School of Mathematics, University of Edinburgh, Edinburgh EH8 9YL, United Kingdom;

3. School of Computing Science, University of Glasgow, Glasgow G12 8QQ, United Kingdom

Abstract

New Exact Approaches Tailored for Kidney Exchange Programs with Hierarchical Objectives Kidney exchange programs increase the rate of living donor kidney transplantation. Whereas effective integer programming models aimed at maximizing the total number of transplants have been proposed in the literature, these cannot always be extended to handle a hierarchy of objectives, which is often a requirement in practice. In “New Algorithms for Hierarchical Optimization in Kidney Exchange Programs,” Delorme, García, Gondzio, Kalcsics, Manlove, and Pettersson introduce a new integer programming framework to solve large-size instances of kidney exchange programs. The authors use an ad hoc preprocessing and a reduced-cost variable fixing algorithm to dramatically decrease the size of the models, and they devise a diving algorithm that exploits the hierarchical structure of the problem to significantly reduce the number of integer programs that need to be solved. They also show that it is possible to transition between models as different layers are traversed in the hierarchy, allowing each layer to be solved with the most effective model. Experiments on three different European kidney exchange programs show that running times can be reduced by up to three orders of magnitude.

Publisher

Institute for Operations Research and the Management Sciences (INFORMS)

Subject

Management Science and Operations Research,Computer Science Applications

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