Clinical measures of balance and gait cannot differentiate somatosensory impairments in people with lower-limb amputation

Abstract

AbstractBackgroundIn addition to a range of functional impairments seen in individuals with a lower-limb amputation, this population is at a substantially elevated risk of falls [1,2]. Studies postulate that the lack of sensory feedback from the prosthetic limb contributes heavily to these impairments, but the extent to which sensation affects functional measures remains unclear [3,4].Research QuestionThe purpose of this study is to determine how sensory impairments in the lower extremities relate to performance with common clinical functional measures of balance and gait in individuals with a lower-limb amputation. Here we evaluate the effects of somatosensory integrity to both clinical and lab measures of static, reactive and dynamic balance, and gait stability.MethodsIn 20 individuals with lower-limb amputation (AMP) and 20 age and gender-matched able-bodied controls (CON), we evaluated the relationship of measures of sensation (pressure, proprioception, and vibration) to measures of balance and gait. Static, reactive, and dynamic balance were assessed using the Sensory Organization Test (SOT), Motor Control Test (MCT), and Functional Gait Assessment (FGA), respectively. Gait stability was assessed through measures of step length asymmetry and step width variability. Sensation was categorized into intact or impaired sensation by pressure thresholds and differences across groups were analyzed.ResultsThere were significant differences between AMP and CON groups for the reliance on vision for static balance in the SOT, MCT, and FGA (p<0.01). Despite these differences across groups, there were no significant differences within the AMP group based on intact or impaired sensation across all functional measures.SignificanceDespite being able to detect differences between able-bodied individuals and individuals with an amputation, these functional measures are unable to distinguish between levels of impairment within participants with an amputation. These findings suggest that more challenging and robust metrics are needed to evaluate the relationship of sensation and function in individuals with an amputation.Research reported in this publication was supported by the National Institutes of Health [NINDS Award Number UH3NS100541 and NICHD Award Number F30HD098794]. The content is solely the responsibility of the authors and does not necessarily reflect the official views of the National Institutes of Health.