Comprehensive genome analysis of 6,000 USA SARS-CoV-2 isolates reveals haplotype signatures and localized transmission patterns by state and by country-Reference-Cited by-同舟云学术

Comprehensive genome analysis of 6,000 USA SARS-CoV-2 isolates reveals haplotype signatures and localized transmission patterns by state and by country

Published:2020-05-26 Issue: Volume: Page:
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Author:

Shen Lishuang,Bard Jennifer Dien,Biegel Jaclyn A.,Judkins Alexander R.,Gai Xiaowu

Abstract

Genomic analysis of SARS-CoV-2 sequences is crucial in determining the effectiveness of prudent safer at home measures in the United States (US). By haplotype analysis of 6,356 US isolates, we identified a pattern of strongly localized outbreaks at the city-, state-, and country-levels, and temporal transmissions. This points to the effectiveness of existing travel restriction policies and public health measures in controlling the transmission of SARS-CoV-2.

Publisher

Cold Spring Harbor Laboratory

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