Author:
Xu Quan,Liu Yueyue,Sun Dawei,Huang Xiaoqian,Li Feihong,Zhai JinCheng,Li Yang,Zhou Qiming,Niu Beifang
Abstract
AbstractSummaryOncoCTMiner is an innovative platform that streamlines precision oncology trial matching by integrating genetic profile analysis and clinical data. It utilizes manual tagging and automated entity recognition to identify six major biomedical concepts within clinical trial records. The platform currently contains a database of over 457,000 clinical trials, enabling quick and advanced search functionalities. Additionally, OncoCTMiner features an automated matching system based on genetic profiles and clinical data, providing real-time matching reports for suitable clinical trials. This platform aims to enhance patient enrollment in precision oncology trials, facilitating the development of personalized cancer therapies.Availability and ImplementationOncoCTMiner is available athttps://oncoctminer.chosenmedinfo.com.Contactniubf@cnic.cnorqimingzhou@chosenmedtech.comSupplementary informationSupplementary data are available atmedRxivonline.Graphic AbstractGraphic abstract:A) OncoCTMiner’s role in precision oncology trial enrollment. B) OncoCTMiner takes clinical and genetic profiles as inputs and utilizes a trial matching and filtering system to generate a report of matched trials. C) Strategy for building the clinical trial eligibility criteria database. D) Automatic matching strategy for genomics-driven oncology trials.
Publisher
Cold Spring Harbor Laboratory
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