Fast and Accurate EEG/MEG BEM-Based Forward Problem Solution for High-Resolution Head Models

Author:

Wartman William A.ORCID,Ponasso Guillermo NuñezORCID,Qi Zhen,Haueisen Jens,Maess Burkhard,Knösche Thomas R.,Weise Konstantin,Noetscher Gregory M.ORCID,Raij Tommi,Makaroff Sergey N.

Abstract

AbstractA BEM (boundary element method) based approach is developed to accurately solve an EEG/MEG forward problem for a modern high-resolution head model in approximately 60 seconds using a common workstation. The method utilizes a charge-based BEM with fast multipole acceleration (BEM-FMM) and a “smart” mesh pre-refinement (calledb-refinement) close to the singular source(s). No costly matrix-filling or direct solution steps typical for the standard BEM are required; the method generates on-skin voltages as well as MEG magnetic fields for high-resolution head models in approximately 60 seconds after initial model assembly. The method is verified both theoretically and experimentally.

Publisher

Cold Spring Harbor Laboratory

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