MDMX (MDM4), a Promising Target for p53 Reactivation Therapy and Beyond
Author:
Publisher
Cold Spring Harbor Laboratory
Subject
General Biochemistry, Genetics and Molecular Biology
Reference96 articles.
1. MdmX is a substrate for the deubiquitinating enzyme USP2a
2. Mdm2 binds p73α without targeting degradation
3. Mice engineered for an obligatory Mdm4 exon skipping express higher levels of the Mdm4-S isoform but exhibit increased p53 activity;Oncogene,2015
4. Significance ofHDMX-S (orMDM4) mRNA splice variant overexpression andHDMX gene amplification on primary soft tissue sarcoma prognosis
5. A Stapled p53 Helix Overcomes HDMX-Mediated Suppression of p53
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