Risk estimates for microcephaly related to Zika virus infection - from French Polynesia to Bahia, Brazil

Author:

Johansson Michael AORCID,Mier-y-Teran-Romero Luis,Reefhuis Jennita,Gilboa Suzanne M,Hills Susan L

Abstract

Zika virus (ZIKV) infection during pregnancy has been linked to birth defects,1 yet the magnitude of risk remains uncertain. A study of the Zika outbreak in French Polynesia estimated that the risk of microcephaly due to ZIKV infection in the first trimester of pregnancy was 0.95% (95% confidence interval: 0.34-1.91%), based on eight microcephaly cases identified retrospectively in a population of approximately 270,000 people with an estimated 66% ZIKV infection rate.2

Publisher

Cold Spring Harbor Laboratory

Reference27 articles.

1. Rasmussen SA , Jamieson DJ , Honein MA , Petersen LR . Zika Virus and Birth Defects - Reviewing the Evidence for Causality. N Engl J Med 2016.

2. Cauchemez S , Besnard M , Bompard P , et al. Association between Zika virus and microcephaly in French Polynesia, 2013–15: a retrospective study. Lancet 2016.

3. Epidemiological Situation of Arboviruses. Sectretary of Health, Bahia; 2016. (http://www.suvisa.ba.gov.br/vigilancia_epidemiologica/consulta_boletim_epidemiologico/4427)

4. Zika Virus Outbreak on Yap Island, Federated States of Micronesia

5. [Microcephaly in Brazil]. Live Births Information System, Ministry of Health, Brazil; 2016. (https://public.tableau.com/profile/bruno.zoca#!/vizhome/Painel2-microcefalia/Painel2-Microcefalia)

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