Abstract
AbstractCandida africanacorresponds to the clade 13 ofCandia albicans. It has been mostly involved in vulvovaginal candidiasis worldwide but few data exist in South America. The aim of our study was to investigate the prevalence ofC. africanain women living in French Guiana. For this, we first set up a fluorescent-intercalating-dye-real time PCR targeting the hyphal wall protein 1 gene. The test was applied to 212C. albicansisolates collected from May to August 2019 from vaginal swabs, allowing the identification of 6 women harboringC. africana(8 isolates). No demographics or clinical-specific features could be demonstrated. Genetic diversity of those isolates was analyzed through multilocus sequence typing and showed that diploid sequence type 182 was predominant (n=6) and allowed the report of a new diploid sequence type.
Publisher
Cold Spring Harbor Laboratory
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