Single Cross-Sectional Analysis; Post-Myocardial Infarction Instrumental & Laboratory changes in Prognosis Behavior

Abstract

AbstractBackgroundCardiovascular events remain one of the frequently reported causes of death globally.AimsAssess the early laboratory and instrumental changes in systemic manner in patients with myocardial infarction (MI).ObjectivesPatients with fresh myocardial infarction that has been occurred in less than 30 days before hospitalization in the rehabilitation hospital.Materials and methodsA single large-scale retrospective cohort sectional study for patients with fresh myocardial infarction for the period 2014-2019, data collected from Mordovia Rehabilitation Hospital. The study involved 154 patients and analysed 76 parameters for each patient. The t test, Pearson’s correlation coefficient, and ROC test have been used. For statistical analysis used Statistica program.ResultsThe sample included 154 patients with a history of fresh myocardial infarction. Of 154. 51(33.11%) female and 103 (66.88 %) males. Chronic heart failure (CHF), which is seen in 42 (27.27 %) patients, 101 (65.58 %) did not have CHF and 11 (7.142 %) missing data. Diabetes mellitus (DM) has been observed in 28 (18.18182 %), 118 (76.62 %) without DM, Hypertension has been seen in 118 (76.62 %), 28 (18.18 %) did not have hypertension, chronic kidney disease (CKD) has been seen in 11 (7.14%) patients, 131 (85.064 %) did not have CKD, Chronic obstructive pulmonary disease (COPD) existed in 14 (9.09 %), 132 (85.71 %) did not have COPD. Post myocardial infarction (MI) CHF has been observed in 108 (70.12987%), 42 (27.27 %) did not have CHF. Post MI arrythmia seen in 50 (32.47%) patients, 99 (64.28 %) did not have arrythmia. Early post MI complication such as aneurysm has been seen in 12 (7.79 %), 138 (89.61 %) did not have aneurysm, Dressler syndrome; pericarditis has been seen in 4 (2.59 %) patients, pneumonitis seen in 1 (0.64 %) patient, and pleuritis have not been seen.ConclusionsSystemic manifestations include kidney function impairment or development of new kidney disease. These changes include an increase in the aorta basement diameter, an increase in the right ventricle size, a decrease in the level of serum red blood cells, the serum potassium level, and serum calcium level, with an increase in the serum myoglobin. The high myoglobin level is associated with the development of chronic heart failure. The higher creatinine level and or LDH is associated with arrythmia development. Hypertension is the predominant concomitant disease in victims of MI. And arrythmia is most commonly reported post-MI complication.OthersFemales are more frequently affected by post-MI urinary tract infection.