Efficient Method for the Preparation of Ozonides Under Dry Conditions

Abstract

Abstract An efficient method for the preparation of ozonides via the reaction of alkenes and ozone under dry conditions is described. The influx of a pre-dried ozone stream into a dichloromethane solution of the olefinic substrates in the presence of molecular sieve 4Å afforded the corresponding ozonides in good to high yields. The reaction in the absence of a molecular sieve gave poor results. The structure of the ozonide was unambiguously confirmed by XRD analysis.