Integrating Pharmacogenomics Into Treatments: Rationales, Current Challenges, and Future Directions

Abstract

Pharmacogenomics is a novel therapeutic concept that essentially focuses on how genes affect the body’s response to different medications. Although it has the potential to revolutionize conventional clinical approaches, the actual implementations in daily practice are not as common or as easy as scientists and physicians had hoped. The disease and cancer management of patients is still very difficult due to the significant interindividual differences in the therapeutic responses observed in clinical practice. Therefore, the goal of this article is to discuss the rationales, challenges, and limitations of pharmacogenomics by analyzing several studies written by experts in diverse fields. Moreover, this article also discusses potential solutions to overcome those challenges and limitations, as well as potential future directions.