Author:
Arifianti Ayun Erwina,Anwar Effionora,Nurjanah Nurjanah
Abstract
<p>Sargassum plagyophyllum from Sargassaceae family contains various bioactive compounds, namely<br />phlorotannin which is reported as an antioxidant and tyrosinase inhibitor. Tyrosinase inhibitor and<br />antioxidant activity from seaweed powder that obtained from seaweed’s slurry have not been reported. Thus,<br />this study was aimed to obtain the best seaweed slurry and powder from S. plagyophyllum based on tyrosinase<br />inhibitor and antioxidant activity, so it can be used as active substance in skin lightening cosmetic formula.<br />S. plagyophyllum which prepared fresh and dried was processed into seaweed slurry and lyophilization<br />to form powder. Antioxidant activity which was determined by 2,2-Diphenyl-1-picrylhydrazyl (DPPH)<br />radical scavenging method found the IC50 values of ascorbic acid was 0.0035 mg/mL; fresh slurry 27.31<br />mg/mL; dried slurry 41.13 mg/mL; fresh powder 2.21 mg/mL; and dried powder 13.18 mg/mL. Moreover,<br />the tyrosinase inhibitory activity which was measured by enzimatic reaction with L-tyrosine as substrate<br />found IC50 values kojic acid 0.0076 mg/mL; fresh powder 4.97 mg/mL; and dried powder 11.35 mg/mL. Seaweed powder obtained from fresh ingredient is the most optimal result based on its tyrosinase inhibitor<br />and antioxidant activity, thus potential to be developed further as active substance for lightening cosmetic<br />formula.<br /><br /></p>
Publisher
Indonesian Society Fisheries Product Processing
Subject
Management, Monitoring, Policy and Law,Geography, Planning and Development
Cited by
6 articles.
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