Recombinant Human Soluble Thrombomodulin Contributes to a Reduction In-Hospital Mortality of Acute Cholangitis with Disseminated Intravascular Coagulation: A Propensity Score Analyses of a Japanese Nationwide Database

Author:

Tarasawa Kunio1,Fujimori Kenji1,Fushimi Kiyohide2

Affiliation:

1. Department of Health Administration and Policy, Tohoku University Graduate School of Medicine

2. Department of Health Policy and Informatics, Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences

Publisher

Tohoku University Medical Press

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

Reference51 articles.

1. Aikawa, N., Shimazaki, S., Yamamoto, Y., Saito, H., Maruyama, I., Ohno, R., Hirayama, A., Aoki, Y. & Aoki, N. (2011) Thrombomodulin alfa in the treatment of infectious patients complicated by disseminated intravascular coagulation: subanalysis from the phase 3 trial. Shock, 35, 349-354.

2. Austin, P.C. (2011) An introduction to propensity score methods for reducing the effects of confounding in observational studies. Multivariate Behav. Res., 46, 399-424.

3. De Backer, D., Biston, P., Devriendt, J., Madl, C., Chochrad, D., Aldecoa, C., Brasseur, A., Defrance, P., Gottignies, P. & Vincent, J.L.; SOAP II Investigators (2010) Comparison of dopamine and norepinephrine in the treatment of shock. N. Engl. J. Med., 362, 779-789.

4. Drake, C. (1993) Effects of misspecification of the propensity score on estimators of treatment effect. Biometrics, 49, 1231-1236.

5. Ely, R., Long, B. & Koyfman, A. (2018) The emergency medicine-focused review of cholangitis. J. Emerg. Med., 54, 64-72.

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