Formation of Novel Pyrido[3′,2′:4,5]Thieno [2,3-e][1,2,4]Triazolo[4,3-c] Pyrimidines and their Acyclic C-Nucleosides Analogues: Synthesis of 3-(Alditol-1-yl)Pyridothienotriazolopyrimidines

Author:

Khattab Ahmed F.1,El-Essawy Farag A.1

Affiliation:

1. Chemistry Department, Faculty of Science, Monoufiya University, Shebin El-Koam, Egypt

Abstract

A series of the hydrazones were prepared by the reaction of 4-hydrazino-7,9-dimethylpyrido[3′,2′:4,5]thieno [2,3-d]pyrimidine (1) with monosaccharides, and their acetylation was studied. The oxidative cyclisation of the hydrazones 3a–c gave 3-(Alditol-1-yl)-pyridothienotriazolopyrimidenes 5a–c, whose acetylation was carried out. Also, oxidative cyclisation of arylidenes 7a,b gave the pyridothienotriazolopyrimidines 8a,b.

Publisher

SAGE Publications

Subject

General Chemistry

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