Affiliation:
1. Chemistry Department, Faculty of Science, Monoufiya University, Shebin El-Koam, Egypt
Abstract
A series of the hydrazones were prepared by the reaction of 4-hydrazino-7,9-dimethylpyrido[3′,2′:4,5]thieno [2,3-d]pyrimidine (1) with monosaccharides, and their acetylation was studied. The oxidative cyclisation of the hydrazones 3a–c gave 3-(Alditol-1-yl)-pyridothienotriazolopyrimidenes 5a–c, whose acetylation was carried out. Also, oxidative cyclisation of arylidenes 7a,b gave the pyridothienotriazolopyrimidines 8a,b.
Cited by
5 articles.
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1. Synthesis of New 1,3,4-Oxadiazol, Thiadiazole, 1,2,4-Triazole, and Arylidene Hydrazide Derivatives of 4-Oxo-1,4-dihydroquinoline with Antimicrobial Evaluation;Journal of Heterocyclic Chemistry;2013-02
2. Three-component synthesis of some 2-amino-5-hydroxy-[1,2,4]triazolo[1,5-a]pyrimidine-6-carbonitriles and 2-(cyanoamino)-4-hydroxypyrimidine-5-carbonitriles;Monatshefte für Chemie - Chemical Monthly;2010-09-08
3. Simple oxidation of pyrimidinylhydrazones to triazolopyrimidines and their inhibition of Shiga toxin trafficking;European Journal of Medicinal Chemistry;2010-01
4. Fused pyridothienopyrimidine heterocycles. 2*. A facile and efficient synthesis of the annelated pyrido[3′,2′:4,5]thieno-[2,3-e]pyrimido[3,2-c]pyrimidones;Chemistry of Heterocyclic Compounds;2009-07
5. Formation of Novel Pyrido[3′,2′:4,5]thieno[2,3-e][1,2,4]triazolo[4,3-c]pyrimidines and Their Acyclic C-Nucleosides Analogues: Synthesis of 2-(Alditol-1-yl)pyridothienotriazolopyrimidines.;ChemInform;2006-04-18