Three-Component One-Pot Synthesis of Unsymmetrical 1,4-dihydropyridine Derivatives in Aqueous Media-Reference-Cited by-同舟云学术

Three-Component One-Pot Synthesis of Unsymmetrical 1,4-dihydropyridine Derivatives in Aqueous Media

Published:2008-08 Issue:8 Volume:2008 Page:441-443
ISSN:1747-5198
Container-title:Journal of Chemical Research
language:en
Short-container-title:Journal of Chemical Research

Author:

Shi Da-Qing¹²,Yu Chen-Xia²,Zhuang Qi-Ya²

Affiliation:

1. College of Chemistry and Chemical Engineering, Key Laboratory of Organic Synthesis of Jiangsu Province, Suzhou University, Suzhou 215123, P.R. China

2. College of Chemistry and Chemical Engineering, Xuzhou Normal University, Xuzhou 221116, P.R. China

Abstract

A series of methyl ethyl 2,6-dimethyl-4-substituted-1,4-dihydropyridine-3,5-dicarboxylates were synthesised by the three-component reaction of aldehydes, ethyl acetoacetate and methyl β-aminocrotonate in the presence of triethylbenzylammonium chloride (TEBAC) in aqueous medium. This method has the advantage of good yields.

Publisher

SAGE Publications

Subject

General Chemistry

Link

http://journals.sagepub.com/doi/pdf/10.3184/030823408X339791

Reference37 articles.

1. Recent Advances in Lewis Acid Catalyzed Diels−Alder Reactions in Aqueous Media

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