Synthesis and Cytotoxicity of Analogues of the Marine Secondary Metabolite, 2-Deoxylapachol-Reference-Cited by-同舟云学术

Synthesis and Cytotoxicity of Analogues of the Marine Secondary Metabolite, 2-Deoxylapachol

Published:2007-12 Issue:12 Volume:2007 Page:677-679
ISSN:1747-5198
Container-title:Journal of Chemical Research
language:en
Short-container-title:Journal of Chemical Research

Author:

Sunassee Suthananda N.¹,van Wyk Albert W.W.¹,Osoniyi Omolaja²,Hendricks Denver T.²,Davies-Coleman Michael T.¹

Affiliation:

1. Department of Chemistry, Rhodes University, Grahamstown, 6140, South Africa

2. Division of Medical Biochemistry, University of Cape Town, Rondebosch, South Africa

Abstract

The syntheses of four 2-substituted 1,4 naphthoquinones, related to the marine natural product 2-deoxylapachol, are reported. All four synthetic compounds were cytotoxic to WHCO1 oesophageal cancer cells.

Publisher

SAGE Publications

Subject

General Chemistry

Link

http://journals.sagepub.com/doi/pdf/10.3184/030823407X270437

Reference20 articles.

1. Geographical distribution and racial disparity in esophageal cancer

2. Antiesophageal Cancer Activity from Southern African Marine Organisms

3. A Cytotoxic and Antifungal 1,4-Naphthoquinone and Related Compounds from a New Zealand Brown Alga, Landsburgia quercifolia

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1. Innovative processes and products involving marine organisms in South Africa;African Journal of Marine Science;2013-09

2. Cytotoxicity of lapachol, β-lapachone and related synthetic 1,4-naphthoquinones against oesophageal cancer cells;European Journal of Medicinal Chemistry;2013-04

3. ChemInform Abstract: Synthesis and Cytotoxicity of Analogues of the Marine Secondary Metabolite, 2-Deoxylapachol.;ChemInform;2008-06-17