Affiliation:
1. College of Chemical Engineering and Materials, Zhejiang University of Technology, Hangzhou 310014, P. R. China
Abstract
A green method for the synthesis of thiazolo[3,2-α]pyridine derivatives via the coupling of malononitrile, an aryl aldehyde and methyl thioglycolate in an ionic liquid has been developed. The advantages of this protocol are that it is non-toxic, no by-products are formed, short reaction times are required and high yields are obtained. Thiazolo [3,2-α]pyridines have important biological and medical applications.
Cited by
6 articles.
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