One-Pot Synthesis of Iodoindolizine Derivatives via a Novel Multicomponent Reaction-Reference-Cited by-同舟云学术

One-Pot Synthesis of Iodoindolizine Derivatives via a Novel Multicomponent Reaction

Published:2013-06 Issue:6 Volume:37 Page:323-326
ISSN:1747-5198
Container-title:Journal of Chemical Research
language:en
Short-container-title:Journal of Chemical Research

Author:

Yan Peiyun¹,Liu Juanjuan¹,Sun Qian¹,Yao Juan¹,Xue Zhiheng¹,Wang Cunde¹

Affiliation:

1. School of Chemistry and Chemical Engineering, Yangzhou University, 180 Siwangting Street, Yangzhou 225002, P. R. China

Abstract

A one-pot reaction was developed to synthesise a variety of 1-iodoindolizines from substituted acetophenone, acetic acid, pyridine, and molecular iodine. The structure of 3-benzoyl-1-iodoindolizine (2a) and 1,3-dibenzoylindolizine (3a) was further confirmed by X-ray single crystal analysis.

Publisher

SAGE Publications

Subject

General Chemistry

Link

http://journals.sagepub.com/doi/pdf/10.3184/174751913X13667371904771

Reference20 articles.

1. Novel indolizine compounds as potent inhibitors of phosphodiesterase IV (PDE4): structure–activity relationship

2. Highly Specific and Broadly Potent Inhibitors of Mammalian Secreted Phospholipases A2

3. A quantitative structure–activity relationship study on a novel class of calcium-entry blockers: 1-[?4-(aminoalkoxy)phenyl?sulphonyl]indolizines

4. Recent Developments of Transition-State Analogue Glycosidase Inhibitors of Non-Natural Product Origin

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