Affiliation:
1. School of Chemical Engineering, Nanjing University of Science &Technology, Nanjing 210094, P.R. China
Abstract
Calcitriol analogues which contained an oxime in the side chain were synthesised in five steps from an intermediate 22-nor Ketone. The key intermediate enones were synthesised by the Wittig–Horner olefination and Wittig olefination respectively. Reduction, oximation, photoisomerisation and deprotection gave the target compounds with the oxime at C-24.
Cited by
3 articles.
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