Poor Antibody Response After Two Doses of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Vaccine in Transplant Recipients-Reference-Cited by-同舟云学术

Poor Antibody Response After Two Doses of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Vaccine in Transplant Recipients

Published:2021-06-24 Issue: Volume: Page:
ISSN:1058-4838
Container-title:Clinical Infectious Diseases
language:en
Short-container-title:

Author:

Mazzola Alessandra¹,Todesco Eve²,Drouin Sarah³,Hazan Fanny⁴,Marot Stéphane²,Thabut Dominique⁵,Varnous Shaida⁴,Soulié Cathia²,Barrou Benoît³,Marcelin Anne-Geneviève²,Conti Filomena¹

Affiliation:

1. Sorbonne Université, Unité Médicale de Transplantation Hépatique, AP-HP, Hôpital Pitié-Salpêtrière, Paris, France

2. Sorbonne Université, INSERM, Institut Pierre Louis d’Epidémiologie et de Santé Publique (iPLESP), AP-HP, Hôpital Pitié-Salpêtrière, Laboratoire de Virologie, Paris, France

3. Sorbonne Université, Service Médico-chirugical de Transplantation rénale, AP-HP, Hôpital Pitié-Salpêtrière, Paris, France

4. Sorbonne Université, Chirurgie Cardiaque et Thoracique, AP-HP, Hôpital Pitié-Salpêtrière, Paris, France

5. Sorbonne Université, Service d’Hépato-gastroentérologie, AP-HP, Hôpital Pitié-Salpêtrière, Paris, France

Abstract

Abstract A low anti-spike antibody response of 28.6% was observed 28 days after BNT162b2 vaccine second dose among 133 solid organ transplant recipients without previous coronavirus disease 2019 (COVID-19). No serious adverse events were recorded. Four severe COVID-19 cases were reported between or after the 2 doses. Our data suggest to change the vaccine strategy.

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Microbiology (medical)

Link

http://academic.oup.com/cid/advance-article-pdf/doi/10.1093/cid/ciab580/39541825/ciab580.pdf

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