Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Viral Load Kinetics in Symptomatic Children, Adolescents, and Adults-Reference-Cited by-同舟云学术

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Viral Load Kinetics in Symptomatic Children, Adolescents, and Adults

Published:2021-05-04 Issue:6 Volume:73 Page:e1384-e1386
ISSN:1058-4838
Container-title:Clinical Infectious Diseases
language:en
Short-container-title:

Author:

Bellon Mathilde¹²,Baggio Stephanie³⁴,Jacquerioz Bausch Frederique²⁵⁶,Spechbach Hervé⁶,Salamun Julien⁶,Genecand Camille⁷,Tardin Aglae⁷,Kaiser Laurent²⁸⁹,L’Huillier Arnaud G⁹¹⁰,Eckerle Isabella¹²⁸⁹

Affiliation:

1. Department of Molecular Medicine and Microbiology, Faculty of Medicine, University of Geneva, Geneva, Switzerland

2. Center for Emerging Viral Diseases, Geneva University Hospitals and University of Geneva, Geneva, Switzerland

3. Division of Prison Health, Geneva University Hospitals, Geneva, Switzerland

4. Office of Corrections, Department of Justice and Home Affairs of the Canton of Zurich, Zurich, Switzerland

5. Division of Tropical and Humanitarian Medicine, Geneva University Hospitals, Geneva, Switzerland

6. Primary Care Division, Geneva University Hospitals and, Geneva, Switzerland

7. Cantonal Health Service, General Directorate for Health, Geneva, Switzerland

8. Division of Infectious Diseases, Department of Medicine, Geneva University Hospitals, Geneva, Switzerland

9. Laboratory of Virology, Division of Laboratory Medicine, Geneva University Hospitals, Geneva, Switzerland

10. Children’s Hospital of Geneva, Geneva University Hospitals, Geneva, Switzerland

Abstract

Abstract SARS-CoV-2 viral load (VL) can serve as a correlate for infectious virus presence and transmission. Viral shedding kinetics over the first week of illness for symptomatic children (n = 279), adolescents (n = 639), and adults (n = 7109) show VLs compatible with infectious virus presence, with slightly lower VL in children than adults.

Funder

Private HUG Foundation

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Microbiology (medical)

Link

http://academic.oup.com/cid/advance-article-pdf/doi/10.1093/cid/ciab396/39308475/ciab396.pdf

Reference14 articles.

1. On the effect of age on the transmission of SARS-CoV-2 in households, schools, and the community;Goldstein;J Infect Dis,2021

2. Changes in contact patterns shape the dynamics of the COVID-19 outbreak in China;Zhang;Science,2020

3. Difference in SARS-CoV-2 attack rate between children and adults may reflect bias;Hyde;Clin Infect Dis,2021