Temozolomide and irinotecan (TEMIRI regimen) as salvage treatment of irinotecan-sensitive advanced colorectal cancer patients bearing MGMT methylation
Author:
Funder
Associazione Italiana per la Ricerca sul Cancro
Ministero della Salute and the Fondazione Piemontese per la Ricerca sul Cancro–ONLUS
Publisher
Elsevier BV
Subject
Oncology,Hematology
Link
http://academic.oup.com/annonc/article-pdf/29/8/1800/25505082/mdy197.pdf
Reference32 articles.
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2. Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents;Esteller;N Engl J Med,2000
3. CpG island hypermethylation of the DNA repair enzyme methyltransferase predicts response to temozolomide in primary gliomas;Paz;Clin Cancer Res,2004
4. Promoter hypermethylation of the DNA repair gene O(6)-methylguanine-DNA methyltransferase is associated with the presence of G:C to A:T transition mutations in p53 in human colorectal tumorigenesis;Esteller;Cancer Res,2001
5. Promoter CpG island hypermethylation of the DNA repair enzyme MGMT predicts clinical response to dacarbazine in a phase II study for metastatic colorectal cancer;Amatu;Clin Cancer Res,2013
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