Phase I dose escalation study of the PI3kinase pathway inhibitor BKM120 and the oral poly (ADP ribose) polymerase (PARP) inhibitor olaparib for the treatment of high-grade serous ovarian and breast cancer

Author:

Matulonis U.A.,Wulf G.M.,Barry W.T.,Birrer M.,Westin S.N.,Farooq S.,Bell-McGuinn K.M.,Obermayer E.,Whalen C.,Spagnoletti T.,Luo W.,Liu H.,Hok R.C.,Aghajanian C.,Solit D.B.,Mills G.B.,Taylor B.S.,Won H.,Berger M.F.,Palakurthi S.,Liu J.,Cantley L.C.,Winer E.

Funder

National Institutes of Health

Ursula Matulonis: Ovarian Cancer Research Foundation, Breast Cancer Research Foundation. William Barry: CJL Foundation. Gordon Mills: Adelson Medical Research Foundation

Gerburg Wulf: Stand Up to Cancer Dream Team Translational Research Grant, a Program of the Entertainment Industry Foundation

Breast Cancer Research Foundation, Mary Kay Ash Foundation, by the Men’s Initiative of the Dana-Farber Harvard Cancer Center and the Breast Cancer Alliance

Shannon Westin: National Institutes of Health

Calabresi Scholar Award, National Institutes of Health

Publisher

Elsevier BV

Subject

Oncology,Hematology

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