Affiliation:
1. Department of Radiology, The Children’s Hospital of Soochow University, Suzhou 215003, China
Abstract
ABSTRACT
Objective
This study was designed to investigate the predictors of bronchopulmonary dysplasia in neonates with respiratory distress syndrome.
Methods
This was a single-center retrospective cohort study conducted between 1 January 2015 and 31 December 2020. A total of 625 neonates with respiratory distress syndrome (RDS) were enrolled. Demographic data, clinical presentations, complications and related treatment information were collected and analyzed. We used bivariate and multivariate logistic-regression analyses to determine significant predictors of bronchopulmonary dysplasia (BPD) in RDS neonates.
Results
In these 625 neonates, 102 (16.3%) of them developed BPD. Bivariate analysis and multivariate logistic-regression analyses revealed that birthweight, gestational age under 32 weeks, duration of oxygen therapy over 10 days, asphyxia, patent ductus arteriosus, transfusion of red blood cells (packed red blood cells) and surfactant use were significantly associated with the development of BPD.
Conclusion
Birthweight, gestational age <32 weeks, total duration of oxygen therapy >10 days, asphyxia, patent ductus arteriosus, need for red blood cell infusion, and the use of pulmonary surfactant were important predictors of BPD in neonates with RDS.
Publisher
Oxford University Press (OUP)
Subject
Infectious Diseases,Pediatrics, Perinatology and Child Health
Cited by
3 articles.
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