Drug-related problems as reason for emergency department visit: 3 years of the FARM-URG registry

Author:

Ruiz-Ramos Jesús1ORCID,Ruiz-Ramos Jesús2,Perrín Rosario Santolaya3,Martín Mª Ángeles García4,Serrano Paloma Sempere5,Riera Margarita Prats6,Valls Montal Camil·la7,Gutiérrez María del Mar García8,Diaz Ana Such9,Pinto Ana de Lorenzo10,Hernanz Beatriz Calderón11,Ramos Nuria Gala12,Díez Montserrat Alonso13,Sánchez Manuel Bonete14,Palomares Ana Gines15,Fernández Nerea15,Ruiz Bárbara Úbeda15,Pardo Ana Arancón4,Cabet Macarena García-Trevijano4,Pérez Álvaro Parea5,Iglesias Manuel Busto5,Borrego Ana Juanes2,Clemente Yolanda Castellanos8,del Mar García Gutiérrez María8,Campaña Juan Manuel Real16,Fernández Beatriz Somoza10,Pérez Marina Fages11,Altuna Ana Ayestarán17,Banzo Josana Fierro17,Candel Gregorio Romero18,Ruiz-Morón Ana Fernández19,García María Muñoz20,Duat Antonia Balet21,Martínez Raquel López22,Alcon Emili Vallve22,Fontelles Gemma Garreta23,García Marta Maialen Mediavilla24,Blanch Cristina Toro25,Pérez Anna Fayet25,Benito Anna Dordá25,Rodríguez Marta26,Albir Mª Jose Company27,Rubio Celia Aparicio27,Torres María Cuenca27,Requejo Carmen Caballero28,Grande Ana Suárez-Lledó29,Casanova Javier Martínez29,Vidal Jaime Barceló30,Alarcón Alicia Rodríguez30,Navarro Mª Rosario Ortíz31,Blanco Cristina Calzón32,Clavero Gemma Morla33,Rodríguez Javier Ramos34,

Affiliation:

1. Servicio de Farmacia, Hospital Santa Creu i Sant Pau , Barcelona , Spain

2. Hospital Santa Cruz y San Pablo

3. H Hospital Príncipe de Asturias

4. Hospital Universitario La Paz

5. Hospitalario Clínico Universitario de Santiago

6. Hospital Can Misses

7. Consorci Hospitalari de Vic

8. Hospital Universitario de Fuenlabrada

9. Hospital Universitario Infanta Leonor

10. Hospital General Universitario Gregorio Marañón

11. Hospital Universitari Son Llàtzer

12. Hospital Comarcal de Manacor

13. Hospital Universitario de Basurto

14. Hospital Universitario San Juan de Alicante

15. Hospital Príncipe de Asturias

16. Hospital Universitario Miguel Servet

17. Hospital de Barcelona

18. Hospital de Hellín

19. Hospital Clínico San Carlos

20. Hospital Ramón y Cajal

21. Althaia, Xarxa Assistencial Univ. de Manresa

22. Hospital Vall d´Hebron

23. Hospital Univ. Mútua Terrassa

24. Hospital Universitario Araba – Santiago

25. Hospital Universitari Dr. Josep Trueta

26. Hospital General Univ. Ciudad Real

27. Hospital de la Ribera

28. Hospital Reina Sofía

29. Hospital Univ. de Bellvitge

30. Hospital del Mar

31. Complejo Hospitalario Univ. de Albacete

32. Hospital Univ. Central de Asturias

33. Hospital Univ. General de Catalunya

34. Hospial Parc Tauli

Abstract

Abstract Objectives Drug-related problems (DRPs) are a well-known cause of emergency department (ED) visits. The objective of the FARM-URG project was to assess the prevalence of DRPs using an annual cross-sectional registry. Herein we report results of the first 3 years, indicating the prevalence of DRPs, drugs involved, and patient characteristics. Methods A point-prevalence multicenter study was conducted across EDs of hospitals in Spain. A specified day and hour was assigned to collect data from all adult patients attending the ED due to DRPs during three consecutive years. Medical records were retrospectively reviewed, with data recorded in REDCap. Key findings Overall, 4752 patients were evaluated at 32 centres, of which 366 (7.7%) visited the ED due to DRPs, with a prevalence ranging from 0 to 16.7%. Antithrombotic drugs accounted for the highest number of DRPs, responsible for 96 (26.8%) episodes. Falls (n = 29; 8.0%) were the most frequent DRPs, followed by haemorrhage (n = 26; 7.12%). Furthermore, 198 (54.2%) reported DRPs were unrelated to medication errors, 80 (21.2%) were overdose errors, and 40 (11.0%) were attributed to poor treatment adherence. Of 366 DRPs-related visits, 54 (14.8%) were due to inappropriately prescribed drugs according to the STOPP-START criteria. Overall, 86 (23.5%) patients revisited the ED within 30 days of discharge, with 34 (9.4%) returning to the ED for new DRPs. Conclusions DRPs are frequently responsible for ED visits and are associated with a considerable percentage of post-discharge visits. The goal of the FARM-URG project is to periodically gather data to design and implement preventive measures.

Funder

Spanish Society of Hospital Pharmacy

Publisher

Oxford University Press (OUP)

Subject

Public Health, Environmental and Occupational Health,Health Policy,Pharmaceutical Science,Pharmacy

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