Tenonplasty Combined With Amniotic Membrane Transplantation for Patients With Severe Ocular Burns Induced Anterior Segment Necrosis

Author:

Peng Wen-yan1,He Li-wen1,Zeng Peng2,Chen Dong-cui1,Zhou Shi-you1

Affiliation:

1. State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China

2. Department of Ophthalmology, Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and GeneRegulation, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China

Abstract

AbstractThis article describes a novel surgical technique for successful repair of intractable corneoscleral necrosis caused by severe ocular burns. In this prospective case series, 19 eyes of 15 consecutive patients with sectional scleral necrosis and persistent corneal epithelial defects were treated with tenonplasty and amniotic membrane transplantation. The main outcome measure was the stability of the ocular surface after reepithelialization and repair of defects. All patients underwent successful combined surgery involving tenonplasty and amniotic membrane transplantation, in which the conjunctival and corneal surfaces were reconstructed. The interval from injury to surgery was 37.4 ± 24.5 days (3–91 days), and the ocular surfaces became stabilized in 82.2 ± 35.4 days (26–156 days, median 87 days). At the final visit, all cases presented with corneal opacity and neovascularization to various degrees. The best-corrected visual acuity decreased from 2.83 ± 1.02 LogMAR preoperatively to 2.87 ± 1.31 LogMAR postoperatively. The results imply that tenonplasty combined with amniotic membrane transplantation could provide vascular supply to the ischemic sclera, repair defects in the conjunctiva, and promote corneal reepithelialization, thus facilitating ocular surface stabilization after burns.

Funder

Guangdong Funding for Scientific and Technological Projects

Fundamental Research Funds of the State Key Laboratory of Ophthalmology

Publisher

Oxford University Press (OUP)

Subject

Rehabilitation,Emergency Medicine,Surgery

Reference29 articles.

1. Chemical injuries of the eye: current concepts in pathophysiology and therapy;Wagoner;Surv Ophthalmol,1997

2. Chemical and thermal injuries of the eyes. Surgical and medical treatment based on clinical and pathophysiological findings;Reim;Arch Soc Esp Oftalmol,2001

3. Burns of the ocular adnexa;White;Curr Opin Ophthalmol,1994

4. Emergency treatment of chemical and thermal eye burns;Kuckelkorn;Acta Ophthalmol Scand,2002

5. A modified symblepharon ring for sutureless amniotic membrane patch to treat acute ocular surface burns;Liang;J Burn Care Res,2012

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