ESC CardioMed is a ground-breaking initiative from European Society of Cardiology together with Oxford University Press that transforms reference publishing in cardiovascular medicine in order to better serve the needs of this rapidly advancing specialty. ESC CardioMed is an encyclopedic online resource covering more than 60 disciplines within cardiology. It will be updated online 3 times a year by the world’s leading clinicians, scientists, and researchers to reflect the latest in global cardiology. More than 1000 of the world’s leading specialists, ranging from researchers to clinicians, have contributed to this vast publication, ensuring a comprehensive and authoritative treatment of the field. ESC CardioMed is highly illustrated, with over 350 videos, helping readers to visualise key concepts. The publication is also linked to the ESC Clinical Practice Guidelines in the European Heart Journal, providing the background information behind clinical practice.