A case of immunoglobulin G conjugated with lactate dehydrogenase, producing both loss of enzyme activity and an abnormal isoenzyme pattern.-Reference-Cited by-同舟云学术

A case of immunoglobulin G conjugated with lactate dehydrogenase, producing both loss of enzyme activity and an abnormal isoenzyme pattern.

Published:1986-07-01 Issue:7 Volume:32 Page:1420-1422
ISSN:0009-9147
Container-title:Clinical Chemistry
language:en
Short-container-title:

Author:

Sudo K,Maekawa M,Watanabe H,Matsumoto K,Mori Y,Sasaki T,Kanno T

Abstract

Abstract We present a patient with an inhibitor of lactate dehydrogenase (LD; EC 1.1.1.27) in serum, who had pericarditis and myocardial hypertrophy. The patient's LD activity in serum was low and the LD isoenzyme pattern was abnormal. The relative molecular mass of this abnormal LD-IgG complex was approximately 490 000. The patient's IgG reacted with all five LD isoenzymes.

Publisher

Oxford University Press (OUP)

Subject

Biochemistry (medical),Clinical Biochemistry

Link

http://academic.oup.com/clinchem/article-pdf/32/7/1420/32772172/clinchem1420.pdf

Cited by 6 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Laboratory and clinical features of abnormal macroenzymes found in human sera;Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics;2015-06

2. A Case of IgG kappa-LD Complex, Producing Long-Term Increase of Enzyme Activity and a Rare Isoenzyme Pattern;Hungarian Medical Journal;2008-09

3. 2.17 Klinische Anwendungen der Protein-Elektrophorese;Elektrophorese;1996-12-31

4. Electrophoretic analysis of enzyme-linked immunoglobulins and their clinical significance;Journal of Chromatography B: Biomedical Sciences and Applications;1991-09

5. Review;Clinical Chemistry and Laboratory Medicine;1990