Critical Evaluation of a New Flame Emission Analysis System, the "Klina Flame"

Abstract

Abstract Recently there have been several advances in instrumental methods for the flame emission analysis of electrolyte cations of clinical significance. Greater precision and increased ease of operation are among today’s clinical requirements. This study compares a new automated flame photometer, "Klina Flame" (Beckman Instruments) with a "Techtron-AA5" atomic absorption emission unit (Varian Instruments) and an "IL 143" flame system (Instrumentation Laboratory). Day-to-day variation between paired data over a three-month period showed comparable and explainable similarities and variations between the three instruments. Results of lithium determinations gave favorable comparison statistics. Long-term stability on all the systems were generally comparable. A comparison of manual vs. automatic modes of dilution with serum samples of various viscosities generally gave predictable variation for instruments of similar quality. The piston dilutor feature of the Klina system seems to prevent the variability seen at higher viscosities when the IL system is used, which has a peristaltic dilutor.