1. Department of Medicine, McMaster University, 1280 Main Street West, Hamilton, Ontario L8S 4L8, Canada
2. Division of Pediatric Cardiology, Department of Pediatrics, Red Cross Children's Hospital, 7700, University of Cape Town, Cape Town, South Africa and Division of Cardiology, Department of Medicine, Groote Schuur Hospital, Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, and Cape Heart Institute, Faculty of Health Sciences, University of Cape Town, Observatory 7945, Cape Town, South Africa
3. Duke Clinical Research Institute, Duke University Medical Center, Durham, NC 27710, USA
4. Universite de Lorraine, Inserm, Centre d’Investigations Cliniques-1433 and Inserm U1116, CHRU Nancy, Nancy 54052, France
5. Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario L8S 4L8, Canada
6. Population Health Research Institute, 20 Copeland Avenue, David Braley Research Building, Hamilton, Ontario L8L 0A3, Canada