1. School of Clinical Medicine, University of Cambridge , Cambridge CB2 0QQ , UK
2. Department of Radiology, Royal Papworth Hospital , Cambridge CB20QQ Cambridge , UK
3. British Heart Foundation Centre for Cardiovascular Science, University of Edinburgh , Edinburgh EH8 9YL , UK
4. Edinburgh Imaging Facility QMRI, University of Edinburgh , Edinburgh EH8 9YL , UK
5. British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge , Cambridge CB2 0QQ , UK
6. British Heart Foundation Centre of Research Excellence, University of Cambridge , Cambridge CB2 0QQ , UK
7. Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge , Cambridge CB2 0QQ , UK
8. NIHR Cambridge Biomedical Research Centre , Cambridge CB2 0QQ , UK