Discussion on “Bayesian meta-analysis of penetrance for cancer risk” by Thanthirige Lakshika M. Ruberu, Danielle Braun, Giovanni Parmigiani, and Swati Biswas

Author:

Ursino Moreno12ORCID,Zohar Sarah12ORCID

Affiliation:

1. Inserm, Université Paris Cité, Sorbonne Université, Centre de Recherche des Cordeliers , F-75006, Paris , France

2. HeKA , Inria Paris, F-75012 Paris ,  France

Abstract

Abstract We congratulate the authors for the new meta-analysis model that accounts for different outcomes. We discuss the modeling choice and the Bayesian setting, specifically, we point out the connection between the Bayesian hierarchical model and a mixed-effect model formulation to subsequently discuss possible future method extensions.

Publisher

Oxford University Press (OUP)

Reference11 articles.

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4. Using dichotomized survival data to construct a prior distribution for a Bayesian seamless phase II/III clinical trial;Duputel;Statistical Methods in Medical Research,2023

5. Random-effects meta-analysis of few studies involving rare events;Günhan;Research Synthesis Methods,2020

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