TMA (trimethylamine), but not its oxide TMAO (trimethylamine-oxide), exerts haemodynamic effects: implications for interpretation of cardiovascular actions of gut microbiome
Author:
Affiliation:
1. Department of Experimental Physiology and Pathophysiology, Laboratory of Centre for Preclinical Research, Medical University of Warsaw, Banacha 1B, Warsaw, Poland
Funder
National Science Centre
Publisher
Oxford University Press (OUP)
Subject
Physiology (medical),Cardiology and Cardiovascular Medicine,Physiology
Link
http://academic.oup.com/cardiovascres/advance-article-pdf/doi/10.1093/cvr/cvz231/29216744/cvz231.pdf
Reference7 articles.
1. Intestinal microbial metabolism of phosphatidylcholine and cardiovascular risk;Tang;N Engl J Med,2013
2. Gut microbiota-dependent trimethylamine N-oxide (TMAO) pathway contributes to both development of renal insufficiency and mortality risk in chronic kidney disease;Tang;Circ Res,2015
3. Organic osmolytes as compatible, metabolic and counteracting cytoprotectants in high osmolarity and other stresses;Yancey;J Exp Biol,2005
4. TMAO: a small molecule of great expectations;Ufnal;Nutrition,2015
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